Multiscale biophysical analysis of nucleolus disassembly during mitosis
An Pham, Madhav Mani, Xiaozhong Wang, Reza Vafabakhsh
PNAS, (2024) WEBStructural basis of TFIIIC-dependent RNA polymerase III transcription initiation
Anna Talyzina, Yan Han, Chiranjib Banerjee, Susan Fishbain, Alexis Reyes, Reza Vafabakhsh, Yuan He
Molecular Cell, (2023) WEBMiddle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor
Ashley N. Ives, Henry A. Dunn, Hamid Samareh Afsari, Henrique dos Santos Seckler, Max J. Foroutan, Erica Chavez, Rafael D. Melani, Ryan T. Fellers, Richard D. LeDuc, Paul M. Thomas, Kirill A. Martemyanov, Neil L. Kelleher, and Reza Vafabakhsh
JACS, (2022) WEBConformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2
Brandon Wey-Hung Liauw, Arash Foroutan, Michael R Schamber, Weifeng Lu, Hamid Samareh Afsari, Reza Vafabakhsh
eLife, e78982 (2022) WEBMechanism of sensitivity modulation in the calcium-sensing receptor via electrostatic tuning
Michael R. Schamber & Reza Vafabakhsh
Nature Communications, 13, 2194 (2022) WEBConformational rearrangement during activation of a metabotropic glutamate receptor
Brandon Wey-Hung Liauw, Hamid Samareh Afsari and Reza Vafabakhsh
Nature Chemical Biology, 17, 291–297 (2021) PDF|WEBMapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling
Lauren M. Adams, Caroline J. DeHart, Bryon S. Drown, Lissa C. Anderson, William Bocik, Emily S. Boja, Tara M. Hiltke, Christopher L. Hendrickson, Henry Rodriguez, Michael Caldwell, Reza Vafabakhsh, Neil L. Kelleher
Journal of Biological Chemistry, 299, 102768 (2022) WEBVisualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
Chiranjib Banerjee, Brandon Wey-Hung Liauw, Reza Vafabakhsh
JoVE, (2022) WEBDNAcycP: a deep learning tool for DNA cyclizability prediction
Keren Li, Matthew Carroll, Reza Vafabakhsh, Xiaozhong A Wang, Ji-Ping Wang
Nucleic Acids Research, 50, 3142–3154, (2022) WEBA viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Li Dai, Digvijay Singh, Suoang Lu, Vishal I. Kottadiel, Reza Vafabakhsh, Marthandan Mahalingam, Yann R. Chemla, Taekjip Ha & Venigalla B. Rao
Nature Communications, 12, 6548 (2021) WEBFRET-Based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices
Elife, 10:e60416 (2021) WEBConformational dynamics of a class C G protein-coupled receptor
Reza Vafabakhsh, Joshua Levitz, Ehud Isacoff,
Nature, 524, 497–501 (2015) PDF|WEBStructural dynamics of potassium-channel gating revealed by single-molecule FRET
Wang S*, Vafabakhsh R*, Borschel WF, Ha T Nichols CG
Nature Structure and Molecular Biology, 23(1):31-36 (2016) PDF|WEBDistinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs
Kim T, Joo C, Seong J, Vafabakhsh R, Botvinick EL, Berns MW, Palmer AE, Wang N, Ha T, Jakobsson E, Sun J, Wang Y
Elife, 4:e04876 (2015) WEBSingle Molecule Packaging Initiation in Real-time by a Viral DNA Packaging Machine from Bacteriophage T4
Vafabakhsh R, Kondabagil K, Earnest T, Lee KS, Zhang Z, Dai L, Dahmen KA, Rao VB, Ha T
Proceedings of the National Academy of Sciences, 111(42):15096-15101 (2014) PDF|WEBDesigning a nine cysteine-less DNA packaging motor from bacteriophage T4 reveals new insights into ATPase structure and function
Kondabagil K, Dai L, Vafabakhsh R, Ha T, Draper B, Rao VB
Virology, 468-470:660-668 (2014) WEBExtreme bendability of DNA less than 100 base pairs long revealed by single-molecule cyclization
Vafabakhsh R, Ha T
Science, 337(6098):1097-1101 (2012) PDF|WEBOne influenza virus particle packages eight unique viral RNAs as shown by FISH analysis
Chou YY*, Vafabakhsh R*, Doğanay S, Gao Q, Ha T, Palese P
Proceedings of the National Academy of Sciences, 109(23):9101-9106 (2012) PDF|WEBThe influenza A virus PB2, PA, NP, and M segments play a pivotal role during genome packaging
Gao Q, Chou YY, Doğanay S, Vafabakhsh R, Ha T, Palese P
Journal of Virology, 86(13):7043-7051 (2012) WEBAntiparallel EmrE exports drugs by exchanging between asymmetric structures
Morrison EA, DeKoster GT, Dutta S, Vafabakhsh R, Clarkson MW, Bahl A, Kern D, Ha T, Henzler-Wildman KA
Nature, 481(7379):45-50 (2011) PDF|WEBA promiscuous DNA packaging machine from bacteriophage T4
Zhang Z, Kottadiel VI, Vafabakhsh R, Dai L, Chemla YR, Ha T, Rao VB
PLoS Biology, 15;9(2):e1000592 (2011) WEBSelf-motile colloidal particles: from directed propulsion to random walk
Howse JR, Jones RA, Ryan AJ, Gough T, Vafabakhsh R, Golestanian R
Physical Review Letters, 99:048102 (2007) PDF|WEB